diff --git a/doc/README_SETUP.md b/doc/README_SETUP.md
index 7d00ed6c5f336f15a10a2e71b843178965f90d15..c0b56bfe627596b4765084d1cf4457acfb7e7545 100644
--- a/doc/README_SETUP.md
+++ b/doc/README_SETUP.md
@@ -37,7 +37,8 @@ variable.
 #### Problems and solutions ####
 
 - Make sure that your conan version supports your XCode version.  A typical symptom of version
-  mismatch is for example conan complaining about incompatible `compiler.version` settings.
+  mismatch is for example conan complaining about incompatible `compiler.version` settings.  You may
+  need to rerun any conan and cmake commands (and delete cache files first) after compiler updates.
 
 ### How to build on Windows